Uncharacterized protein (Fragment) OS=Macaca mulatta GN=ITPK1 PE=4 in breast cancer gene 1 protein OS=Macaca mulatta GN=KIAA1967 PE=2 SV=1
Figure 1. Schematic of data sources for My Cancer Genome. Curated assertions on the My Cancer Genome website are housed within a Knowledge Management System (KMS) created through a partnership with GenomOncology that serves as a warehouse of biomarker, disease, and drug ontologies; biomarker-driven cancer clinical trials; therapeutic, prognostic, and diagnostic assertions; and unstructured
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0.1766. 636. Blcap, bladder cancer associated protein, 1142, 31.93, 31.22, 30.05, 31.07, 6203 Itpk1, inositol 1,3,4-triphosphate 5/6 kinase, 2396, 37.96, 27.55, 42.27, 35.93 63, U-CAN, Uppsala Umeå Comprehensive Cancer Consortium, Sweden ITPK1, inositol-tetrakisphosphate 1-kise [Source:HGNC Symbol;Acc:6177], 0.4082 Cancer susceptibility candidate 1 OS=Rattus norvegicus GN=Casc1 PE=2 SV=1 Protein Itpk1 (Fragment) OS=Rattus norvegicus GN=Itpk1 PE=4 SV=2 Uncharacterized protein (Fragment) OS=Macaca mulatta GN=ITPK1 PE=4 in breast cancer gene 1 protein OS=Macaca mulatta GN=KIAA1967 PE=2 SV=1 för ett annat kinas som kallas ITPK1 , vilket är ett inositol 1, 3, 4-trisfosfat 5/6-kinas och inte I de flesta fall orsakar ITP3K-uttryck att cancer blir mer aggressiv. SP4, PLEKHA7, ITPK1 / C14orf109 och regionerna 10p11.23, 10q11.21, 6p23 och Ökade risker för cancer för släktingar till bröstcancerfall med mycket tidig ITP 1/1863 - ITPK 1/1864 - ITPS 1/1865 - ITP (olika betydelser) 1/1866 - ITRE Guilds 11/15068 - International Agency for Research on Cancer 11/15069 ITPK1 : Inositol 1, 3, 4-Triphosphate 5/6 Kinase ; NM_014216.3; fw: IndexTerm TP73 : Tumor Protein p73 ; NM_005427.2; NM_001126240.1, som ATP6V1B2, GRM7, SP4, PLEKHA7, ITPK1 / C14orf109 och regioner 10p11.23, 10q11.21, 6p23 och 2q22.1 (tabellerna 5 och 6 och kompletterande filer) . Three additional loci are linked to the SLC24A3, ITPK1 and GJA1 genes, which all have a function in cellular ion homeostasis. More unexpectedly, many genes Cancer, hematologisk utveckling, immunologiska och inflammatoriska Dessutom finns cg05284742 relaterad till NO 2- exponering i ITPK1; denna gen This is NOT a known cancer gene.
2000-05-01 · itpk1_arath
This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries.
Whether you or someone you love has cancer, knowing what to ex 11 Apr 2019 2Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA ITPK1. ITPK1_HUMAN Inositol-tetrakisphosphate 1-kinase.
ITPK1 is the kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. It may also act as an isomerase that interconverts the inositol tetraphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of A
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Cancer Gene Census 3. CancerGenes 4.
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Nine genes were identified overexpressed in both basal-like breast cancer cells and BRCA1 mutated cells. ITPK1, 1.982, 0.536, CENPN, 2.008, 0.964.
It is not found in the Cancer Gene Census . Curated gene. This is NOT an expert curated gene .
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Cell atlas. Showing subcellular location of ITPK1. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies.
It is involved in inositol signalling pathways which regulate the conductance of calcium-activated chloride channels, and therefore could be relevant in the study of cystic fibrosis. ITPK1 mutation reduces labeling of InsP 6 by 50%, with concomitant accumulation of d / l ‐Ins(3,4,5,6)P 4, but because it does so without affecting the level of Ins(1,3,4,5,6)P 5 (Figures 5a and S6a) suggests that ITPK1 probably does not act as an Ins(1,3,4,5,6)P 5 1‐phosphatase.
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ITPK1 (Inositol-Tetrakisphosphate 1-Kinase) is a Protein Coding gene. Diseases associated with ITPK1 include Neural Tube Defects. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Inositol phosphate metabolism.
Phosphorylates Ins(3,4,5, Breast cancer is the most common cancer among women. Although the breast cancer mortality rates have fallen over the past few decades – thanks to early detection and treatment improvements – the disease remains the second leading cause of cancer death in females. CGAP: ITPK1 : Familial Cancer Database: ITPK1 * This gene is included in those cancer gene databases..